Melanosis of the urinary bladder with associated urinary tract infection

Melanosis of the bladder is an exceedingly rare benign condition that can mimic more serious urothelial pathologies. Here, we analyze the clinical presentation, associated symptomatology, and follow-up of a patient presenting with melanosis and associated urinary tract infection. This patient is a 72-year-old male undergoing workup for gross hematuria, lower urinary tract symptoms, and recurrent urinary infections. We subsequently discuss two additional incidental findings of melanosis and associated urinary tract infection at our institution, and introduce novel context for this condition that currently lacks a standardized management protocol. To our knowledge, this is the first case series on melanosis vesicae.