Primordial Odontogenic Tumour - A Case Report

Area of Science:

• Odontogenesis and Dental Pathology
• Oral and Maxillofacial Surgery
• Tumor Histopathology

Background:

• Primordial odontogenic tumour (POT) is a newly recognized entity in the WHO 2017 classification.
• Odontogenic tumors encompass a diverse group of lesions with varying clinical and histological features.
• Accurate diagnosis is crucial for appropriate management and to avoid overtreatment.

Purpose of the Study:

• To report a rare case of primordial odontogenic tumour (POT) in the posterior mandible of a pediatric patient.
• To contribute to the understanding of POT by presenting clinical and histopathological findings.
• To aid in differentiating POT from other odontogenic tumors.

Main Methods:

• Case presentation of a 9-year-old male with mandibular swelling.
• Histopathological examination of the resected tumor.
• Review and collation of clinical and histopathological data from 25 previously reported POT cases.

Main Results:

• The patient presented with a left posterior mandibular swelling.
• Histopathology revealed myxoid connective tissue stroma and stratified epithelium without rete pegs.
• The diagnosis of primordial odontogenic tumor was confirmed after enucleation.

Conclusions:

• This case highlights the occurrence of POT in the mandible.
• Detailed histopathological analysis is key to diagnosing POT.
• Distinguishing POT from other odontogenic tumors is essential for optimal patient management.