Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ventilatory Modes01:14

Ventilatory Modes

54
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
54
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

97
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
97

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nitric oxide in Extracorporeal Membrane Oxygenation Sweep Gas Promotes Oxygenator Longevity: A Technical Case Report.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

Extracorporeal life support in adult critically ill patients: mechanisms of benefit in respiratory and cardiac failure.

American journal of respiratory and critical care medicine·2026
Same author

Extracorporeal Membrane Oxygenation Support Before Pediatric Heart Transplantation: A Comparison of Two Eras.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

National Outcomes of Pediatric Patients Bridged to Heart Transplant with the Heartmate 3 Ventricular Assist Device.

The Annals of thoracic surgery·2026
Same author

Is There a Unified Etiology of Hypoplastic Left Heart Syndrome? Evaluating Genetic, Structural, and Hemodynamic Models of Disease Initiation.

Pathophysiology : the official journal of the International Society for Pathophysiology·2026
Same author

Pediatric Heart Transplant Outcomes Using COVID-19-Positive Donors in the United States.

The Annals of thoracic surgery·2026

Related Experiment Video

Updated: May 29, 2025

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

9.3K

Conversion technique of pulsatile-to-continuous flow single ventricular assist device.

Yuriy Stukov1, Jeffrey P Jacobs1, Kayla V Lucas1

  • 1Congenital Heart Center, Division of Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA.

Multimedia Manual of Cardiothoracic Surgery : MMCTS
|February 5, 2025
PubMed
Summary

For congenital heart disease patients needing a ventricular assist device, switching from pulsatile to continuous flow can resolve severe hemolysis. This case report details the technique for this critical intervention.

Keywords:
Berlin Heart VAD implantationECMOEXCOR pediatricPaediatric cardiac surgeryVAD

More Related Videos

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.2K
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.5K

Related Experiment Videos

Last Updated: May 29, 2025

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

9.3K
Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.2K
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.5K

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Pediatric Cardiology

Background:

  • Congenital heart disease patients with complex anatomy may require ventricular assist devices (VADs) as a bridge to transplant.
  • Pulsatile paracorporeal VADs, like the Berlin Heart EXCOR, are used for complex cases, mimicking natural heart function.
  • The pulsatile displacement pump design of the Berlin Heart EXCOR carries a risk of increased hemolysis.

Purpose of the Study:

  • To present a case report of severe hemolysis in a patient supported by a pulsatile VAD.
  • To describe the step-by-step technique for converting a pulsatile flow VAD to a continuous flow VAD.
  • To highlight continuous flow VADs as a potential solution for managing pump-induced hemolysis.

Main Methods:

  • Case report of a patient experiencing severe hemolysis on a Berlin Heart EXCOR VAD.
  • Detailed description of the surgical and technical procedure for transitioning from pulsatile to continuous flow support.
  • Monitoring of hemolysis markers and patient status post-conversion.

Main Results:

  • The patient presented with severe hemolysis attributed to the pulsatile displacement pump.
  • Successful conversion from the pulsatile Berlin Heart EXCOR to a continuous flow VAD was performed.
  • Resolution of severe hemolysis following the device exchange.

Conclusions:

  • Switching to a continuous flow ventricular assist device can be an effective strategy to manage severe hemolysis in patients supported by pulsatile devices.
  • This case demonstrates the feasibility and benefit of VAD type conversion in complex pediatric cardiac support.
  • Careful patient selection and procedural technique are crucial for successful VAD conversion.