High-Sensitivity Cardiac Troponin Assays: From Implementation to Resource Utilization and Cost Effectiveness
Hong-Kee Lee1,2, Cian P McCarthy3, Allan S Jaffe4,5
1Department of Pathology and Laboratory Medicine, Endeavor Health, Evanston, IL, United States.
Background:
Cardiac troponin is the gold-standard biomarker for the evaluation of patients with suspected acute myocardial infarction (MI). Improvements in assay technology have led to high-sensitivity cardiac troponin assays that, when incorporated into accelerated diagnostic pathways, may rapidly diagnose or exclude acute MI more efficiently than conventional troponin assays.
Content:
In this narrative review, we provide practical suggestions for implementing high-sensitivity cardiac troponin assays, review accelerated diagnostic pathways incorporating these assays, and review the impact of these assays on resource utilization and cost-effectiveness in relation to the evaluation of individuals with possible acute MI.
Summary:
An increasing number of hospitals are transitioning to high-sensitivity cardiac troponin assays. This narrative review provides an overview of the potential benefits of this transition.
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