Application of omics technology in ecotoxicology of arthropod in farmland

Arthropods, abundant in farmland, have unique biological traits that make them valuable for studying the ecotoxicological impacts of pollutants. Recent advancements in multi-omics technologies have enhanced their use in assessing pollution risks and understanding toxicity mechanisms. This article reviews recent developments in applying omics technologies-genomics, transcriptomics, proteomics, metabolomics, and meta-omics-to ecotoxicological research on farmland arthropods. Agricultural arthropods manage genes and proteins, such as metallothioneins, antioxidant enzyme systems, heat shock proteins, cytochrome P450, carboxylesterases, and glutathione S-transferases, for detoxification and antioxidant purposes. They adjust amino acid, sugar, and lipid metabolism to counteract pollutant-induced energy drain and modify gut microbiota to aid in detoxification. This study advocates for enhanced analysis of compound pollution and emerging pollutants using multi-omics, especially meta-omics, to clarify the toxicological mechanisms underlying arthropod responses to these pollutants. Furthermore, it underscores the urgent need for subsequent gene function mining and validation to support biological control strategies and promote sustainable agricultural practices. The findings of this research provide significant insights into the toxicological impacts and mechanisms of pollutants within farmland ecosystems, thereby contributing to the preservation of arthropod diversity.