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Human Parechovirus Infection in an Infant Presenting with Hyperferritinemia

Kayla Rose McConnaha1, Zachary Kenneth Bracken1, Rebecca Rose Mastey1

  • 1Medical College of Wisconsin-Green Bay, Green Bay, Wisconsin.

WMJ : Official Publication of the State Medical Society of Wisconsin
|February 5, 2025
PubMed

Insights

Human parechovirus (HPeV) infections in infants can cause severe illness, including hyperinflammation. Intravenous immunoglobulin (IVIG) may be a potential treatment for HPeV-induced hyperferritinemia and cytokine storm syndrome.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Immunology

Background:

  • Human parechovirus (HPeV) is a known pathogen causing severe infections in infants.
  • HPeV infections can manifest with serious complications like encephalitis, hepatitis, sepsis, and organ dysfunction.
Abstract

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