Comparative blanching activities of locally manufactured proprietary fluocinolone acetonide topical preparations

The blanching activities and hence the bio-availabilities of the cream and ointment formulations of Synalar and Cortoderm (fluocinolone acetonide 0,025%) were evaluated using an occluded and unoccluded blanching assay. Statistical analysis showed significant differences between similar formulations of fluocinolone acetonide.