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Valvular Heart Disease-A New Evolving Paradigm
Rick A Nishimura1, Steve R Ommen1, Joseph A Dearani1
1Department of Cardiovascular Medicine and the Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN.
Insights
Valvular heart disease impacts many, but early detection and intervention can improve quality of life and longevity. Recognizing subtle signs of valve disease is crucial for timely treatment and better patient outcomes.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Valvular Heart Disease
Background:
- Valvular heart disease is a prevalent cardiovascular condition associated with significant morbidity and mortality.
- Despite advances, nearly half of patients who could benefit from interventions are underdiagnosed or not referred.
- Early identification is key to restoring quality of life and increasing longevity.
Purpose of the Study:
- To review current diagnostic and therapeutic advancements in valvular heart disease.
- To emphasize the importance of early recognition and intervention, even before symptom onset.
- To highlight the role of shared decision-making in patient management.
Main Methods:
- Review of noninvasive diagnostic tools, including echocardiography.
- Discussion of surgical and catheter-based therapeutic options.
- Analysis of national guidelines for intervention timing.
Main Results:
- Echocardiography confirms valve disease presence and severity.
- Surgical and catheter-based therapies offer improved outcomes.
- Emerging evidence suggests early intervention can prevent ventricular dysfunction.
Conclusions:
- Early diagnosis and intervention in valvular heart disease are critical for improved patient outcomes.
- Shared decision-making, considering patient needs and expectations, is essential for treatment planning.
- Prompt recognition of valve disease, even in asymptomatic patients, is increasingly important.
Abstract:
Valvular heart disease is one of the most common cardiovascular diseases today and may result in severe limiting symptoms, a shortened lifespan, and, in some cases, sudden death. It is important to identify significant valve disease because intervention can restore quality of life and in many instances increase longevity. In most patients, the diagnosis of significant valvular heart disease can be made on the basis of a physical examination, yet nearly half of the patients who could benefit from interventions are not being recognized or referred. There have been major improvements in both the diagnosis and treatment of patients with valvular heart disease, with noninvasive echocardiography available to confirm the presence and severity of valve disease, better and more durable surgical procedures, and the advent of catheter-based therapies. There are now national guidelines to aid clinicians in the optimal timing of the intervention, which are presented. However, it is now recognized that the long-standing volume or pressure overload from valve disease can result in incipient ventricular dysfunction even before the onset of symptoms or a drop in ejection fraction; therefore, there is an impetus to recognize and to treat these patients earlier and earlier in the disease natural history. A shared decision-making process should play a key role in the final decision for therapy, outlining the goals and risks of possible intervention coupled with the patient's own needs and expectations.
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