Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alternating skew deviation: 47 patients.

J R Keane

    Neurology
    |May 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Alternating hypertropia, a form of ocular skew deviation, affects 12% of patients. Lesions in the pretectal region or brainstem are common causes, with the exact mechanism still under investigation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Visual loss in cysticercosis: analysis of 23 patients.

    Neurology·2001
    Same author

    Dueling doctors.

    Southern medical journal·2000
    Same author

    Hypertensive brain stem encephalopathy.

    AJNR. American journal of neuroradiology·2000
    Same author

    Combined VIth and XIIth cranial nerve palsies: a clival syndrome.

    Neurology·2000
    Same author

    Hypertensive brainstem encephalopathy: three cases presenting with severe brainstem edema.

    Neurology·1999
    Same author

    Most diabetic third nerve palsies are peripheral.

    Neurology·1998

    Area of Science:

    • Neuro-ophthalmology
    • Neurology
    • Ophthalmology

    Background:

    • Ocular skew deviation is a vertical misalignment of the eyes.
    • Alternating hypertropia, where one eye is higher than the other and switches with gaze, is a less common presentation.

    Purpose of the Study:

    • To investigate the prevalence and causes of alternating hypertropia in patients with ocular skew deviation.
    • To explore potential mechanisms underlying alternating hypertropia.

    Main Methods:

    • Retrospective analysis of 408 patients diagnosed with ocular skew deviation.
    • Clinical examination and neuroimaging to identify lesion locations.
    • Review of patient history and neurological signs.

    Main Results:

    Related Experiment Videos

    • 12% (47 out of 408) of patients presented with alternating hypertropia.
    • Pretectal lesions accounted for 29 cases, while 5 cases showed lower brainstem involvement.
    • Common etiologies included acute hydrocephalus, tumors, strokes, and multiple sclerosis (MS).
    • Posterior fossa involvement was uncertain in 13 cases.

    Conclusions:

    • Alternating hypertropia is an uncommon but significant finding in ocular skew deviation.
    • Pretectal and brainstem lesions are frequently implicated.
    • The precise mechanism remains elusive but likely involves vestibular pathways to ocular motor neurons.