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Related Experiment Video

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The Healthcare Integrated Research Database (HIRD) as a Real-World Data Source for Pharmacoepidemiologic Research.

John J Barron1, Vincent J Willey1, Brett T Doherty1

  • 1Carelon Research, Wilmington, Delaware, USA.

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|February 5, 2025
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Summary

The Healthcare Integrated Research Database (HIRD) is a large real-world data source with over 91 million individuals. It supports diverse health research, including safety and outcomes studies, by providing comprehensive, linked health information.

Keywords:
CarelonEHRElevance HealthHIRDHealthcare Integrated Research DatabaseSDoHclaimsdatabasereal‐world datareal‐world evidence

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Area of Science:

  • Health Informatics
  • Real-World Data Research
  • Biomedical Data Science

Background:

  • The Healthcare Integrated Research Database (HIRD) is an extensive real-world data (RWD) repository.
  • It aggregates demographic and healthcare data from individuals enrolled in Elevance Health insurance plans.
  • Data availability spans from January 2006 to the present, with monthly updates.

Purpose of the Study:

  • To describe the Healthcare Integrated Research Database (HIRD) as a valuable resource for health-related research.
  • To highlight the scope and characteristics of the HIRD population and data.
  • To underscore its utility in generating real-world evidence.

Main Methods:

  • Utilizes routinely updated RWD, including health insurance claims.
  • Data encompasses individuals residing across the United States.
  • Supports data traceability, linkage with external sources, and family member connections.

Main Results:

  • As of July 2024, HIRD contains over 91 million individuals with medical benefits, with over 24 million actively enrolled.
  • The population has a median age of 36 years, with 50% identifying as female.
  • Median continuous enrollment is 2.0 years overall and 3.8 years for actively enrolled individuals.

Conclusions:

  • HIRD is a reliable source for generating real-world evidence.
  • It facilitates various research types, including safety studies, comparative effectiveness, and health economics and outcomes research.
  • The database's comprehensive nature and linkage capabilities enhance its research utility.