Circumscribed Alopecia Areata Incognita and Response to Tofacitinib
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View abstract on PubMed
Summary
This summary is machine-generated.Alopecia areata incognita (AAI) is a debated condition. A rare circumscribed AAI variant was successfully treated with oral tofacitinib when corticosteroids failed, suggesting a new therapeutic option.
Area Of Science
- Dermatology
- Trichology
Background
- Alopecia areata incognita (AAI) is a debated hair loss condition.
- Circumscribed AAI, a localized variant, is rarely documented.
Purpose Of The Study
- To report an unusual case of circumscribed AAI.
- To evaluate the efficacy of oral tofacitinib in a refractory case.
Main Methods
- A 21-year-old woman with circumscribed AAI was treated with oral tofacitinib 5 mg twice daily.
- Diagnosis was confirmed via trichoscopy showing typical AAI features.
Main Results
- The patient experienced a sustained positive response to oral tofacitinib.
- Conventional treatments like dexamethasone led to relapses and weight gain.
Conclusions
- Oral tofacitinib is a potential therapeutic option for AAI cases unresponsive to corticosteroids.
- This case highlights tofacitinib's efficacy in refractory circumscribed AAI.
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