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Updated: May 29, 2025

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
Mastic Kidney: A Rare Radiological Feature
Mariana Salvado de Morais1, Sofia Cunha1, Íris Galvão1
1Internal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT.
Abstract:
This case emphasizes the importance of considering tuberculosis (TB) in the differential diagnosis of complex kidney imaging findings. We report a case of a 43-year-old male patient from India who presented with a five-day history of fever and vomiting. Laboratory results revealed metabolic acidosis, anemia, acute kidney injury, and elevated inflammatory markers. A computed tomography urogram demonstrated significant findings: minimal parenchymal remnants in the left kidney replaced by caliectasis, ureteral pyelitis, and retroperitoneal lymphadenopathy, including calcified nodes in the right kidney. The diagnosis of genitourinary TB was made after bronchoalveolar lavage and urine samples confirmed the presence of Mycobacterium tuberculosis. The imaging findings were consistent with "mastic kidney," a rare radiological sign of renal TB, characterized by extensive parenchymal destruction. First-line antituberculous therapy was initiated, leading to clinical improvement. This case highlights the critical role of early diagnosis and the importance of considering TB in patients with multisystem involvement. "Mastic kidney," though rare, remains a key radiological sign of renal TB, underscoring the need for heightened clinical awareness in suspected cases of extrapulmonary TB.
Insights
Tuberculosis (TB) can present with complex kidney imaging findings. Early diagnosis of genitourinary TB is crucial, especially with the rare "mastic kidney" sign indicating extensive renal destruction.
Area of Science:
- Nephrology
- Infectious Diseases
- Radiology
Background:
- Genitourinary tuberculosis (TB) is a significant global health concern.
- Complex kidney imaging findings necessitate a broad differential diagnosis.
- Extrapulmonary TB can manifest with diverse clinical presentations.
Observation:
- A 43-year-old male presented with fever, vomiting, acute kidney injury, and anemia.
- CT urogram revealed extensive left kidney destruction, ureteral pyelitis, and retroperitoneal lymphadenopathy.
- Calcified lymph nodes were noted in the right kidney, suggestive of chronic inflammation.
Findings:
- Diagnosis of genitourinary TB confirmed by positive Mycobacterium tuberculosis in bronchoalveolar lavage and urine.
- Imaging findings consistent with "mastic kidney," a rare sign of advanced renal TB with parenchymal destruction.
- Patient showed clinical improvement after initiating first-line antituberculous therapy.
Implications:
- Highlights the importance of considering TB in the differential diagnosis of complex renal pathologies.
- Emphasizes the diagnostic value of recognizing the "mastic kidney" radiological sign.
- Underscores the need for heightened clinical awareness for extrapulmonary TB in endemic regions.
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