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Unveiling and Validating a Modified Method to Assess Cervical Sagittal Alignment as an Effective Substitute for
Wenpeng Li1,2, Qiwei Wang2, Qiancheng Zhao2
1Department of Neurosurgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Clinics in Orthopedic Surgery
|February 6, 2025
Summary
The SYS-G angle is a reliable method for assessing cervical sagittal alignment when the C7 lower endplate is unclear. This study establishes its reference ranges in Chinese adults for clinical application.
Area of Science:
- Orthopedics
- Radiology
- Spine Surgery
Background:
- Cervical sagittal alignment is crucial for spinal health.
- Assessing alignment often relies on the C2-C7 Cobb method, which can be limited by C7 endplate visibility.
- A modified parameter, the SYS-G angle, was developed to address these limitations.
Purpose of the Study:
- To validate the SYS-G angle as a substitute for the C2-C7 Cobb method in assessing cervical sagittal alignment.
- To determine the reference range of the SYS-G angle in a large cohort of asymptomatic Chinese adults.
Main Methods:
- Retrospective analysis of lateral cervical spine X-rays from 825 asymptomatic Chinese adults.
- Comparison of C7 lower endplate visibility with other landmarks.
- Measurement of C2-6 Cobb angle, SYS-G angle, and C2-7 Cobb angle.
- Assessment of intra- and interobserver reliability and efficacy of the SYS-G angle.
- Analysis of factors affecting C7 endplate visibility and correlation with SYS-G angle.
Main Results:
- C7 lower endplate visibility was significantly reduced compared to C6 and C7 upper endplates.
- Age, weight, BMI, and male sex negatively impacted C7 lower endplate visibility.
- The SYS-G angle demonstrated strong correlation with the C2-7 Cobb angle and excellent efficacy in evaluating cervical lordosis.
- Reference ranges for the SYS-G angle were established, showing positive correlation with age and higher values in men.
Conclusions:
- The SYS-G angle is a reliable alternative for cervical sagittal morphology assessment, especially when C7 endplate visibility is compromised.
- Established reference ranges provide valuable data for clinical guidance in managing cervical spine disorders.
- The study highlights the influence of demographic factors on C7 endplate visibility and SYS-G angle values.

