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Anti-Mi-2-positive dermatomyositis with subclinical cardiac involvement

Simon Goller1, Tassilo Dege1, Marc Schmalzing2

  • 1Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

European Journal of Dermatology : EJD
|February 6, 2025
PubMed
Abstract

No abstract available in PubMed .

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Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
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