Related Experiment Video

Updated: May 29, 2025

Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice
09:00

Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice

Published on: August 2, 2018

8.1K

A new 'mini-CRISPR' flexes its editing power in monkey muscles

Jennifer Couzin-Frankel

    Science (New York, N.Y.)
    |February 6, 2025
    PubMed
    Summary

    Researchers have developed a smaller DNA-slicing tool. This innovation allows for broader tissue targeting to address a wider range of diseases.

    More Related Videos

    CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.07:46

    CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.

    Published on: December 11, 2020

    5.8K
    Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms09:51

    Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

    Published on: May 25, 2018

    33.7K

    Related Concept Videos

    CRISPR01:59

    CRISPR

    Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
    49.1K
    Conservative Site-specific Recombination and Phase Variation02:53

    Conservative Site-specific Recombination and Phase Variation

    Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
    The recognition sites for Cre recombinase called LoxP...
    5.9K