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Updated: Jul 5, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
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Vancomycin Concentrations in Umbilical Cord Blood After Intrapartum Exposure

Sarah A Coggins1, Kelly C Wade, Kevin M Watt

  • 1Division of Neonatology, Clinical Futures, and the Division of Infectious Diseases, Children's Hospital of Philadelphia, and the Department of Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania; and the Division of Clinical Pharmacology, Department of Pediatrics, University of Utah, Salt Lake City, Utah.

Obstetrics and Gynecology
|February 6, 2025
PubMed
Summary

Maternal vancomycin dosing for Group B Streptococcus (GBS) prophylaxis effectively transfers to neonates. Most newborns had cord blood vancomycin levels exceeding the GBS minimum inhibitory concentration (MIC) breakpoint, ensuring adequate protection.

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