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Published on: December 14, 2020
A Standardized Approach to Performing and Interpreting Functional Lumen Imaging Probe Panometry for Esophageal
Dustin A Carlson1, John E Pandolfino1, Rena Yadlapati2
1Kenneth C. Griffin Esophageal Center of Northwestern Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
This study standardized Functional Lumen Imaging Probe (FLIP) panometry interpretation for esophageal motility disorders. A consensus established clear guidelines for procedure and diagnosis, improving clinical application.
Area of Science:
- Gastroenterology
- Esophageal Physiology
- Diagnostic Endoscopy
Background:
- Functional Lumen Imaging Probe (FLIP) panometry assesses esophagogastric junction opening and esophageal motility.
- It is increasingly used in comprehensive esophageal motility assessments.
- Standardization is needed for consistent interpretation and updated classification.
Purpose of the Study:
- To establish a standardized approach and vocabulary for FLIP panometry procedure and interpretation.
- To update the esophageal motility classification scheme based on expert consensus.
Main Methods:
- A modified Delphi consensus process involving 19 FLIP panometry experts.
- Multiple rounds of voting on statement appropriateness (1-9 scale) and face-to-face discussions.
- Selection of 40 statements for the Dallas Consensus, focusing on protocol, interpretation, and classification.
Main Results:
- The Dallas Consensus includes statements on FLIP panometry protocol and interpretation.
- Key findings emphasize interpreting FLIP panometry in clinical context (100% agreement).
- A normal FLIP panometry classification suggests major motor disorders are unlikely (94% agreement), and nonspastic EGJ outflow obstruction is supported by diminished contractility with reduced opening (94% agreement).
Conclusions:
- The standardized approach facilitates broader clinical use of FLIP panometry.
- The Dallas Consensus provides a framework for consistent performance and interpretation.
- This standardization aims to improve the diagnosis and management of esophageal motility disorders.
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