Related Experiment Video
Updated: May 29, 2025

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
Published on: April 21, 2015
Primary Intestinal NK/T-cell Lymphoma Masquerading as Crohn's Disease: A Report of Two Cases
Priya Jayakumar1, Lavleen Singh1, Vineet Ahuja2
1Pathology, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.
Abstract:
Extranodal NK/T-cell lymphoma (ENKTL) most commonly affects the upper aerodigestive tract. Primary intestinal NK/T-cell lymphoma is extremely rare and poses a formidable challenge for both the gastroenterologists and pathologists. We herein report two cases of ENKTL. On histopathological and immunohistochemical examination of the resected specimens, a final diagnosis of primary intestinal NK/T-cell lymphoma was made. Due to significant overlap in clinical, endoscopic, and histopathological findings, this entity is often misdiagnosed as Crohn's disease. Multiple endoscopic biopsies with the use of an elaborate immunohistochemical panel can help in diagnosis at an early stage, thereby improving the management and prognosis.
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