Renomegaly as a Presentation of T-Acute Lymphoblastic Leukemia
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View abstract on PubMed
Summary
This summary is machine-generated.A 15-year-old boy with bilateral renomegaly showed kidney infiltration by blasts. Treatment led to the resolution of enlarged kidneys and reduced metabolic activity, indicating successful therapy for this condition.
Area Of Science
- Pediatric Nephrology
- Oncology
- Diagnostic Imaging
Background
- Bilateral renomegaly can be a presenting sign in pediatric hematologic malignancies.
- Interstitial infiltration of the kidneys by blasts requires accurate diagnosis and monitoring.
Purpose Of The Study
- To report a case of bilateral renomegaly secondary to blast infiltration.
- To illustrate the utility of [18F]FDG PET/CT in assessing treatment response.
Main Methods
- A 15-year-old male patient presented with nausea and was found to have bilateral renomegaly.
- Kidney biopsy confirmed interstitial infiltration by blasts.
- [18F]FDG PET/CT scans were performed before and after induction therapy.
Main Results
- Kidney biopsy revealed interstitial infiltration by blasts.
- [18F]FDG PET/CT demonstrated diffuse uptake in bilaterally enlarged kidneys.
- Post-induction therapy, repeat [18F]FDG PET/CT showed resolution of renomegaly and decreased standardized uptake value (SUV).
Conclusions
- Bilateral renomegaly in a pediatric patient can be caused by leukemic infiltration.
- [18F]FDG PET/CT is a valuable tool for monitoring treatment response in such cases.
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