Related Experiment Video
Updated: Jul 28, 2026
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Resolution of subretinal fluid in intractable central serous chorioretinopathy with high-dose intravitreal
Jonathan B Lin1, Loh-Shan B Leung1
1Byers Eye Institute at Stanford University, Palo Alto, CA, USA.
Purpose:
To report an unusual case of a patient with intractable central serous chorioretinopathy with a dramatic treatment response to high-dose intravitreal aflibercept.
Methods:
Retrospective case report.
Results:
A 40-year-old female patient presented with decreased vision after use of intranasal fluticasone and recent life stressors and was diagnosed with central serous chorioretinopathy. Over a three-year period, she underwent numerous therapies, including seven sessions of photodynamic therapy, intravitreal bevacizumab, standard-dose intravitreal aflibercept, intravitreal faricimab, oral eplerenone, oral acetazolamide, and topical ketorolac, with minimal to no treatment response. After a single treatment with high-dose intravitreal aflibercept, 8 mg, she achieved resolution of subretinal fluid.
Conclusion:
High-dose intravitreal aflibercept may have a role in management of treatment-resistant central serous chorioretinopathy; further studies are needed.
More Related Videos
11:03Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
Published on: January 22, 2018
11:20Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
