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Both response effort and current intensity affect self-stimulation train duration thresholds.

R A Frank, H P Williams

    Pharmacology, Biochemistry, and Behavior
    |April 1, 1985
    PubMed
    Summary
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    Brain stimulation reward (BSR) thresholds can be misleading. Both reward intensity and performance effort equally influence self-stimulation thresholds, challenging their use as pure measures of reward. Further research is needed.

    Area of Science:

    • Neuroscience
    • Behavioral Neuroscience
    • Psychology

    Background:

    • Self-stimulation thresholds are commonly used to assess brain stimulation reward (BSR).
    • These measures assume independence from performance factors, an assumption rarely tested.
    • The influence of performance variables on BSR thresholds requires explicit investigation.

    Purpose of the Study:

    • To investigate the combined effects of response effort and current intensity on self-stimulation thresholds.
    • To determine if performance variables significantly alter BSR threshold measurements.
    • To assess the relative contribution of reward intensity versus performance effort on threshold determination.

    Main Methods:

    • Factorial combination of three stimulation current levels and three lever weightings (response effort).

    Related Experiment Videos

  • Determination of train duration thresholds, defined as 50% of maximum response rates, for each condition.
  • Analysis of how changes in current intensity and response effort impact self-stimulation thresholds.

    • Main Results:

    • Both current intensity and response effort significantly shifted train duration thresholds.
    • The magnitude of shifts caused by current intensity and response effort were approximately equal.
    • Self-stimulation response functions were similarly affected by reward and performance manipulations.

    Conclusions:

    • Caution is advised when interpreting self-stimulation threshold data for BSR measurement.
    • Performance factors, such as response effort, can significantly confound BSR threshold interpretations.
    • Thresholds may not solely reflect reward value but also the cost of performance.