Related Experiment Video
Updated: May 29, 2025

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Brain health: A concern for anaesthesiologists and intensivists
Vincent Bonhomme1, Christian Putensen1, Bernd W Böttiger1
1From the Department of Anesthesia and Intensive Care Medicine (VB), Anesthesia and Perioperative Neuroscience Laboratory, GIGA-Consciousness Thematic Unit, GIGA-Research, Liege University Hospital, Liege, Belgium (VB, AD), Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn (CP), University of Cologne, Medical Faculty, and Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany (BWB), Department of Anesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands (MFS), Division of Anaesthesia, Pain Medicine and Intensive Care, Imperial College London, Royal Brompton & Harefield Hospitals, Guy's & St. Thomas' NHS, London, United Kingdom (NM), Department of Anaesthesia and Intensive Care, Semmelweis University, Budapest, Hungary (NM), Anaesthesiology Department, Hospital Universitario Fundacion Alcorcon, Alcorcon, Spain (DA), General Intensive Care Unit, Division of Anesthesiology and Intensive Care, Soroka University Medical Center, Ben Gurion University of the Negev, Beer- Sheva, Israel (EB), Department of Anesthesiology, Rambam Healthcare Campus (AR), The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel (AR), University Department of Anesthesia and Intensive Care Medicine, CHR Citadelle (AD), Department of Anesthesia and Intensive Care Medicine, Liege University Hospital, Liege, Belgium (AD), Department of Intensive Care Medicine, Erasme Hospital - University Hospital of Brussels, Université Libre de Bruxelles, Brussels, Belgium (EB), Department of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel (SS), Coma Science Group, GIGA-Consciousness, Liege University, Belgium, and Centre du Cerveau, Liege University Hospital, Liege, Belgium (PC), Institute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (AM), Dipartimento di Scienze Chirurgiche Diagnostiche e Integrate, University of Genoa (CR), IRCCS Policlinico San Martino, Genoa, Italy (CR), Department of Anaesthesiology and Intensive Care, Cerrahpasa Faculty of Medicine, Istanbul University- Cerrahpasa, Istanbul, Turkey (OKD), Department of Neurology, Liege University Hospital, Liege, Belgium (JL), Emergency Department, University Hospital Zurich, Zurich, Switzerland (MIC), Department of Anesthesia, Adrz-Erasmus MC, Goes, the Netherlands (JCDG), Department of Anesthesiology, Weill Cornell Medicine, New York, USA (JCDG, LE), Department of Anesthesiology and Perioperative Medicine, University Hospital of Brussels, Brussels, Belgium (NN), University Hospitals of Geneva, Geneva, Switzerland (LV), Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands (AA, MS), Department of Anesthesiology and Intensive Care Medicine | CCM | CVK, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany (IA, FY), Department of Anesthesiology, Cliniques universitaires Saint Luc (QS, MM), Institut de Recherche Expérimentale et Clinique (MM, CK), Institute of Neuroscience, Université catholique de Louvain, Brussels, Belgium (MM, CK), Department of Anaesthesiology, Auckland City Hospital, Auckland, New Zealand (DC), Department of Critical Care, School of Medicine, University of Melbourne (LE), Department of Anaesthesia and Acute Pain Medicine, St. Vincent's Hospital Melbourne, Melbourne, Australia (LE), Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, USA (SV), Department of Anaesthesiology-Critical Care, AZ Sint-Jan, Bruges, Belgium (SS), Hospital La Conception and Aix-Marseille University, Marseille, France (NB), Tip Fakültesi, Cerrahi Tip Bilimleri, Anesteziyoloji ve Reanimasyon, Gazi University, Ankara, Turkey (DAO), Anesthesiology Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates (FAL), Department of Clinical Neurophysiology, University of Twente and Medisch Spectrum Twente, Enschede (MvP), Neurological Institute, Cleveland Clinic Akron General Hospital, Fairlawn, Ohio, USA (GWJH), Division of Anesthesiology, Intensive Care and Pain Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia (AK), Department of Anesthesia (DBS), The Applied Neurophysiology Lab, Rambam Healthcare Campus, Haifa, Israel (GS), Department of Anaesthesia and Intensive Care, Nykoebing Hospital, University of Southern Denmark, Denmark (FR) and Department of Anesthesiology, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium (CK).
Abstract:
Damage to the brain can have disastrous and long-lasting consequences. The European Society of Anaesthesiology and Intensive Care (ESAIC) is aware of the importance of taking good care of the brain, both of patients and of anaesthesia and intensive care unit (ICU) caregivers, and has organised a complete learning track on brain health to bring this concern to the attention of practitioners. This learning track included an online Focus Meeting on Brain Health (November 25, 2023). We here provide readers with a digest of the information that was delivered during that meeting in an opinion paper driven by the authors' own reading of the literature. It is divided according to the meeting's sessions, including how to improve the health of an injured brain, how to keep a young or old brain healthy, how to keep a healthy adult brain unimpaired, how monitoring can impact brain health in the operating room and in the intensive care unit, and how to keep the anaesthesia and ICU caregivers' brain healthy. Each part is a brief and focused summary. The main delivered messages are that the management of injured brain patients involves an adequate choice of sedation, adequate brain monitoring, and focused attention to specific points depending on the underlying pathology; that several measures can be undertaken to protect the brain of the very young needing anaesthesia; that it is possible to detect older patients at risk of postoperative neurocognitive disorders, and that dedicated perioperative management by a multidisciplinary expert team may improve their outcomes; that apparently healthy adult brains may suffer during anaesthesia; that the electroencephalogram may track peri-operative brain dysfunction, and that female patients should be given special care in this respect; that multimodal brain monitoring helps to detect pathological processes and to maintain brain homeostasis; and that burnout in anaesthesiologists can be effectively fought using personal, organisational, managerial and legal approaches.
More Related Videos
14:52Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
Published on: January 13, 2018
08:23Adaptation of Microelectrode Array Technology for the Study of Anesthesia-induced Neurotoxicity in the Intact Piglet Brain
Published on: May 12, 2018
Related Concept Videos
Inhalational Anesthetics: Overview
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...