Related Experiment Video
Updated: May 29, 2025
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Breaking the frailty cycle with rehabilitation programs. A systematic review and meta-analysis of randomized
Bruna da Silveira1, Amanda Farias E Farias2, Victória Brum3
1Physiotherapist, PhD student at the Post-graduate Program in Human Movement Sciences at the State University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Purpose:
To investigate how different sets of rehabilitation programs can contribute to breaking the frailty cycle.
Methods:
Systematic review with meta-analysis of randomized controlled trials that investigated the effects of rehabilitation programs for adults with FS. Search for references on Embase, PEDro, SciELO, Web Of Science, Pubmed, EBSCO and Scopus, published until September 2024. Methodological quality was assessed with the PEDro scale, risk of bias with ROB 2.0, and certainty of evidence with the GRADE approach.
Results:
Thirty-four studies (34) were included, with high methodological quality and a low risk of bias. There is significant evidence that rehabilitation programs were able to improve performance in activities of daily living (SMD = 0.83; 95%CI: 0.26, 1.40; p = 0.004; low certainty), lower extremity function and mobility (SMD = 0.63; 95%CI: 0.40, 0.86; p < 0.001; moderate certainty) and gait speed (SMD = 1.07; 95%CI: 0.17, 1.97; p = 0.002; low certainty), reducing frailty score (SMD = -1.57; 95%CI: -2.97, -0.17; p ≤ 0.001; very low certainty) and prevalence of frailty (RR = 0.76; 95%CI: 0.65, 0.89; p = 0.006; very low certainty), with minimal to no reports of adverse effects.
Conclusions:
Rehabilitation programs consisting of multicomponent moderate-intensity physical exercise associated with nutritional monitoring, cognitive training, educational strategies, and medical and social support are effective to break the frailty cycle. Implications for rehabilitationRehabilitation programs for older people can prevent and reverse pre-frailty.Performance, mobility, gait speed and strength improve with rehabilitation programs.Rehabilitation professionals should considerer these key components when designing rehabilitation programs for the frail and pre-frail older people: multicomponent exercises, nutrition, and cognitive training.Rehabilitation professionals should be aware that adherence is the main barrier in older peoples frailty rehabilitation programs.
More Related Videos
Related Concept Videos
01:19Restorative Care
01:30Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...