Related Experiment Video
Updated: Jan 26, 2026

Flypub To Study Ethanol Induced Behavioral Disinhibition and Sensitization
Published on: May 18, 2020
[HPLC studies on the distribution behavior of guanyl- and N-phenylguanylhydrazone derivatives]
Abstract:
The article in hand presents first HPLC studies on the distribution behaviour of guanylic and N-phenylguanylic hydrazone derivates. The chromatographic parameters of compounds, which had been separated at NH2-columns by 0.06 mol X 1(-1) Na2HPO4 buffer/methanole (30 : 70), could be identified, and the k'/rates could be utilized for the calculation of the coefficient of distribution. As a result of performed calculations of the correlation, it could be proved that the log. P rates which had been ascertained by the HPLC method, been determined by the shaked flash method and been calculated acc. to Leo, correlate to the 1% significant level.
Related Concept Videos
Drug Distribution: Volume of Distribution
What is Behavior?
F Distribution
Variation: Normal Distribution, Range, and Standard Deviation
Volume of Distribution
Uniform Distribution
Two essential properties of this distribution are

