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A Rare Malignancy; Primary Peritoneal Serous Carcinoma in Men with 18F-FDG PET/CT and Histopathology
Büşra Özdemir Günay1, Burak Günay2, Nuray Can3
1Giresun Training and Research Hospital, Clinic of Nuclear Medicine, Giresun, Türkiye.
Abstract:
Primary peritoneal serous carcinoma (PPSC) is a rare malignancy that mostly affects women. In males, there are only few reports in the literature. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is useful for evaluating the origin of the tumor, its extent, and distant metastasis. Moreover, 18F-FDG PET/CT was helpful in distinguishing between PPSC and peritoneal carcinomatosis. We present a case of PPSC on 18F-FDG PET/CT in a male with histopathological correlation.
Insights
Primary peritoneal serous carcinoma (PPSC) is rare in males. 18F-FDG PET/CT imaging aids in diagnosing PPSC, determining tumor extent, and differentiating it from peritoneal carcinomatosis in male patients.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Primary peritoneal serous carcinoma (PPSC) is a rare malignancy predominantly affecting women.
- PPSC in males is exceptionally rare, with limited case reports available in medical literature.
- Accurate diagnosis and staging of PPSC are crucial for patient management.
Purpose of the Study:
- To report a rare case of primary peritoneal serous carcinoma in a male patient.
- To illustrate the utility of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in evaluating PPSC in males.
- To demonstrate the role of 18F-FDG PET/CT in distinguishing PPSC from peritoneal carcinomatosis.
Main Methods:
- Case presentation of a male patient diagnosed with PPSC.
- Utilized 18F-FDG PET/CT for tumor origin evaluation, staging, and metastasis assessment.
- Histopathological correlation to confirm the diagnosis.
Main Results:
- 18F-FDG PET/CT provided valuable information regarding the tumor's origin and extent.
- The imaging modality assisted in differentiating PPSC from peritoneal carcinomatosis.
- Histopathology confirmed the diagnosis of PPSC.
Conclusions:
- 18F-FDG PET/CT is a useful tool for evaluating primary peritoneal serous carcinoma, even in rare male cases.
- This imaging technique aids in staging and distinguishing PPSC from other peritoneal malignancies.
- Further research may explore the specific role of 18F-FDG PET/CT in male PPSC management.
