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Updated: May 29, 2025

Preparation of Acute Human Hippocampal Slices for Electrophysiological Recordings
Published on: May 7, 2020
Cognitive impairment in epilepsy progression: Adult neurogenesis loss at critical window
1Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China; Institute of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Abstract:
The mechanisms underlying cognitive impairment in epilepsy remain poorly understood. Ammothumkandy et al.1 reveal that the loss of adult immature neurons correlates with auditory verbal learning deficits in human mesial temporal lobe epilepsy during a critical disease period, underscoring the pivotal role of adult neurogenesis in specific cognitive domain.
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