Related Experiment Video
Updated: May 29, 2025

An Acupoint Catgut-embedding Therapy for Treating Obesity
Published on: April 4, 2025
Nutrient-Stimulating Hormone-Based Therapies for Obesity
Cagney Cristancho1, Dong Wook Kim2, Caroline M Apovian2
1Center for Weight Management and Wellness, Division of Endocrinology, Diabetes and Hypertension, Brigham & Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA.
Abstract:
Obesity is a chronic disease with an increasing worldwide prevalence. Improving obesity is of paramount importance given its association with conditions such as type 2 diabetes, cardiovascular disease, and cancer among others. In the last decade, a new class of highly efficacious medications called nutrient-stimulating hormone (NuSH) therapies has emerged. This article highlights the effectiveness of the FDA-approved NuSH-based therapies-liraglutide, semaglutide, and tirzepatide-in long-term weight management. Ongoing trials are exploring novel mechanisms of action to simultaneously target multiple receptors involved in appetite and energy regulation, promising further advancements and additional treatment options in the field of obesity management.
More Related Videos
06:28A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
11:36A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
Published on: April 28, 2016
Related Concept Videos
Regulation of Food Intake
Hormonal Regulation
Regulation of Metabolism
Regulation of Hormone Secretion
Humoral...
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
Binge Eating Disorders