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Updated: May 29, 2025

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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
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A comprehensive analysis of deep learning and transfer learning techniques for skin cancer classification
Manishi Shakya1, Ravindra Patel2, Sunil Joshi3
1Department of Computer Application, UIT RGPV, Bhopal, MP, India. manishirgpv@gmail.com.
Scientific Reports
|February 7, 2025
Summary
This study enhances melanoma diagnosis by using deep learning models to classify skin lesions. Combining ResNet-18 and MobileNet with SVM achieved 92.87% accuracy in identifying skin cancer.
Area of Science:
- Dermatology and Medical Imaging
- Artificial Intelligence in Healthcare
- Computational Pathology
Background:
- Early and accurate melanoma diagnosis is crucial but challenging due to diverse skin lesion characteristics.
- Deep learning offers promising solutions for automated skin cancer image classification.
- Existing methods require evaluation for improved diagnostic accuracy.
Purpose of the Study:
- To investigate and compare deep learning approaches for classifying dermoscopic images of skin lesions.
- To identify an effective deep learning strategy for distinguishing between benign and malignant skin cancers.
- To evaluate the performance of various pre-trained networks and machine learning classifiers.
Main Methods:
- Three deep learning strategies were evaluated: fine-tuned pre-trained networks (VGG19, ResNet18, MobileNet_V2), pre-trained networks as feature extractors with machine learning classifiers (SVM, DT, Naïve Bayes, KNN), and combined feature extraction.
- Image preprocessing included scaling, denoising, and enhancement, followed by segmentation using the active contour approach.
- The ISIC 2018 dataset, comprising 3300 skin disease images, was used for training (80%) and testing (20%).
Main Results:
- The combined approach using ResNet-18 and MobileNet_V2 as feature extractors, concatenated and fed into a Support Vector Machine (SVM) classifier, yielded the highest accuracy.
- This hybrid model achieved a maximum classification accuracy of 92.87% on the ISIC 2018 dataset.
- Different training parameters such as epoch, batch size, and learning rate were optimized for each approach.
Conclusions:
- Combining deep learning feature extraction (ResNet-18, MobileNet_V2) with SVM classification offers a highly effective method for melanoma detection.
- The developed approach demonstrates significant potential for improving the accuracy and efficiency of early skin cancer diagnosis.
- Further research can explore ensemble methods and advanced architectures for even greater diagnostic precision.

