Brown-McLean syndrome secondary keratoconus

Area of Science:

• Ophthalmology
• Corneal Diseases

Background:

• Brown-McLean Syndrome (BMS) is a rare condition causing peripheral corneal edema, typically after intraocular surgery.
• This case presents a unique instance of unilateral BMS in an 18-year-old male without a history of ocular surgery or trauma.

Purpose of the Study:

• To report a unique case of Brown-McLean Syndrome (BMS) co-occurring with keratoconus.
• To explore the potential relationship between BMS and keratoconus.

Main Methods:

• Case report of an 18-year-old male presenting with unilateral poor vision and peripheral corneal edema.
• Clinical examination including corneal topography to diagnose BMS and keratoconus.
• Absence of ocular surgery, trauma, or systemic diseases was noted.

Main Results:

• Unilateral peripheral corneal edema (2-4 mm from limbus) was observed in the right eye.
• Corneal topography revealed concurrent keratoconus as an incidental finding.
• The patient had no history of ocular surgery, trauma, or systemic disease.

Conclusions:

• BMS should be considered in the differential diagnosis of peripheral corneal edema, even without prior ocular surgery or trauma.
• A potential link between long-term corneal edema in BMS and the development of keratoconus is proposed.
• Thorough clinical evaluation and long-term follow-up are essential for managing such cases.