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Related Concept Videos

Colloids and Suspensions01:17

Colloids and Suspensions

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Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
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Steady, Laminar Flow Between Parallel Plates01:17

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Steady Flow of a Fluid Stream01:27

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Consider a control volume, such as a pipe with solid boundaries, through which fluid flows and changes direction due to the impulse exerted by the resulting force from the pipe walls. In steady flow, the mass of fluid entering the control volume at a given time, t, with velocity v1, is equal to the mass leaving after infinitesimal time dt, with velocity v2.
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Colloids03:22

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Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
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Capillarity describes the movement of liquid in small spaces without external forces acting on it. The capillarity is driven by surface tension and adhesive interactions between the liquid and surrounding solid surfaces. This effect is often seen in narrow tubes, porous materials, and fine particles.
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Related Experiment Video

Updated: May 29, 2025

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures
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Surface-Driven Particle Dynamics: Sequential Synchronization of Colloidal Flow Attempted in a Static Fluidic

Hyeonseol Kim1, Abbas Ali2, Yumin Kang2

  • 1National Nanofab Center (NNFC), Daejeon 34141, Republic of Korea.

ACS Applied Materials & Interfaces
|February 8, 2025
PubMed
Summary
This summary is machine-generated.

Researchers developed a flowless micropump for precise micro-object control using micromagnetic patterns. This platform enables direct and indirect manipulation of microcargo, advancing applications in drug delivery and microfluidics.

Keywords:
cargo manipulationmagnetic fieldmagnetic particlesmicrofluidicsthin-film pattern

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Area of Science:

  • Colloid and surface chemistry
  • Microfluidics and lab-on-a-chip technologies
  • Biotechnology and nanotechnology

Background:

  • Precise control of micro-objects in microsystems is crucial for applications like drug delivery, microfluidics, and nanotechnology.
  • Conventional fluidic components often limit the precision and scope of micro-object manipulation.
  • Developing novel platforms for advanced microcargo manipulation is essential for scientific progress.

Purpose of the Study:

  • To introduce a novel cargo-manipulating platform, the flowless micropump, that utilizes micromagnetic patterns and fluid flow.
  • To demonstrate two distinct modes of microcargo manipulation: direct and indirect.
  • To establish a programmable platform for diverse experimental purposes in microscale systems.

Main Methods:

  • The flowless micropump platform integrates actuation particles and control targets within a chip, eliminating external fluidic components.
  • Direct manipulation of nonmagnetic cargo (e.g., cells) is achieved through coordinated particle collisions guided by specific wall structures.
  • Indirect manipulation of particles is enabled by localized fluid flow generated by patterned magnetic structures (railway-track and conductor patterns).

Main Results:

  • The platform demonstrated precise and agile control of microcargo, including cells (MCF-7, THP-1) and polymer beads.
  • Two manipulation modes were successfully implemented: direct control via particle collisions and indirect control via localized fluid flow.
  • Effective microcargo manipulation was achieved at frequencies of 1-3 Hz with a magnetic field strength of 10 mT.

Conclusions:

  • The developed flowless micropump platform offers a programmable and versatile tool for micro-object manipulation.
  • The platform's ability to generate colloidal and localized fluid flow using magnetic patterns shows significant promise for various applications.
  • Potential applications include drug screening, cell-cell interaction studies, and organoid-on-chip research.