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Updated: May 1, 2026

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Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
Published on: September 10, 2018
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Bottom-Up Metasurfaces for Biotechnological Applications.
Francesca Petronella1, Federica Zaccagnini2, Maria Laura Sforza2
1National Research Council of Italy, Institute of Crystallography CNR-IC, Montelibretti Division, Area territoriale di Ricerca di Roma, Strada Provinciale 35d, Rome, n. 9 - 00010, Italy.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|February 8, 2025
Summary
This review explores hybrid metasurfaces fabricated using bottom-up colloidal nanoparticle methods, offering a scalable alternative to traditional nanofabrication for advanced optical applications.
Area of Science:
- Nanophotonics and Plasmonics
- Materials Science
- Biotechnology
Background:
- Metasurfaces, 2D counterparts of metamaterials, manipulate light for applications like optical communications and biosensing.
- Traditional metasurface fabrication relies on precise nanofabrication of meta-atoms, which is effort-intensive and costly.
- Bottom-up methods using colloidal nanoparticles offer a promising alternative for scalable and cost-effective metasurface production.
Purpose of the Study:
- To review recent advances in bottom-up fabrication of hybrid metasurfaces.
- To highlight applications of plasmonic nanoparticle-based metasurfaces, particularly in biotechnology.
- To explore perspectives for disordered metasurface design and applications.
Main Methods:
- Review of literature on bottom-up fabrication of hybrid metasurfaces using colloidal nanoparticles.
- Emphasis on plasmonic nanoparticle self-assembly for disordered metasurfaces.
- Discussion of hybrid approaches combining bottom-up and top-down methods for organized metasurfaces.
Main Results:
- Bottom-up methods enable rapid, cost-effective fabrication of disordered metasurfaces.
- Plasmonic nanoparticle metasurfaces exhibit diverse applications, especially in biotechnology.
- Hybrid fabrication strategies can yield organized metasurface structures.
Conclusions:
- Bottom-up fabrication with colloidal nanoparticles accelerates metasurface technology development.
- Disordered metasurfaces present unique opportunities for future design and applications.
- Hybrid metasurfaces bridge the gap between bottom-up scalability and top-down precision.
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