Fluorescence-based nanocomposite sensor for meclofenamic acid detection in dairy products

This study introduces a novel nanocomposite fluorescent probe (N-GQDs@Cit-HA@MIP) for the sensitive and selective detection of meclofenamic acid, a non-steroidal anti-inflammatory drug, in dairy products. The probe combines nitrogen-doped graphene quantum dots, citrate-functionalized hydroxyapatite, and a molecularly imprinted polymer, achieving a detection limit of 0.03 μg L^-1 and recoveries of 93.2-99.9 % with RSDs below 3.1 %. The sensor offers superior sensitivity and reduced analysis time compared to chromatographic methods. Furthermore, its compatibility with smartphone-based detection systems highlights its potential for rapid on-site food safety monitoring.