Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Systemic reactions associated with polyisocyanate exposure.

J Nielsen, C Sangö, G Winroth

    Scandinavian Journal of Work, Environment & Health
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    B-Cell-Activating Factor Levels Are Associated With Antibody-Mediated Histological Damage in Kidney Transplantation.

    Transplantation proceedings·2016
    Same author

    Population balance models of autonomous microbial oscillations.

    Journal of biotechnology·1995
    Same author

    Induction and repression of alpha-amylase production in batch and continuous cultures of Aspergillus oryzae.

    Microbiology (Reading, England)·1995
    Same author

    Continuous cultivation of Penicillium chrysogenum. Growth on glucose and penicillin production.

    Journal of biotechnology·1995
    Same author

    Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway.

    Nature·1995
    Same author

    Mechanical and electromyographic analysis of reciprocal inhibition at the human ankle joint.

    Journal of neurophysiology·1995
    Same journal

    Employer-provided bicycle benefit and changes in commuting and overall physical activity: A quasi-experiment among Finnish municipal employees.

    Scandinavian journal of work, environment & health·2026
    Same journal

    Genomic insights into somatic mutations from occupational exposure to low-dose ionizing radiation.

    Scandinavian journal of work, environment & health·2026
    Same journal

    Mental health problems and suicidal behaviors in person-related work: a Swedish register-based cohort study.

    Scandinavian journal of work, environment & health·2026
    Same journal

    Relative risk and excess fraction of preterm birth across maternal occupation and industry: a Danish nationwide register-based cohort study of employed pregnant women.

    Scandinavian journal of work, environment & health·2026
    Same journal

    Job strain and ischemic heart disease: the balance of methodological bias and implications for prevention. Response to: Bonde JP et al. The demands-control-support work stress model and risk of ischemic heart disease: causal inference based on observational epidemiology.

    Scandinavian journal of work, environment & health·2026
    Same journal

    Employment and working conditions and risk of suicidal behaviors: a systematic review and meta-analysis of longitudinal studies.

    Scandinavian journal of work, environment & health·2026
    See all related articles

    Spray painters exposed to high levels of polyisocyanates may experience flu-like symptoms and respiratory issues. This study highlights the health risks associated with isocyanate exposure in occupational settings.

    Area of Science:

    • Occupational Health
    • Toxicology
    • Immunology

    Background:

    • Polyisocyanates, commonly found in varnishes, are used in spray-painting applications.
    • Occupational exposure to isocyanates can lead to respiratory and systemic health issues.

    Observation:

    • A spray painter presented with acute symptoms including chills, fever, dyspnea, wheezing, headache, arthralgia, and leukocytosis after varnish aerosol exposure.
    • High levels of polyisocyanates (4.2 mg/m3 TWA) were detected in the workroom air, significantly exceeding toluene diisocyanate monomer levels (0.03 mg/m3 TWA).

    Findings:

    • Immunologic studies showed an elevated serum immunoglobulin G (IgG) level.
    • No specific antibodies against isocyanates conjugated to human serum albumin were detected, suggesting a non-IgE mediated or different immunologic response.

    Related Experiment Videos

    Implications:

    • This case underscores the potential for polyisocyanate aerosols to cause acute, flu-like illness in spray painters.
    • Monitoring and controlling workplace exposure to polyisocyanates is crucial for preventing occupational health problems.
    • Further research may be needed to elucidate the specific immunologic mechanisms underlying these reactions to isocyanates.