Assessing Racial and Ethnic Health Disparities in a Diverse Cohort with Pediatric Inflammatory Bowel Disease

Ashleigh Watson1, Chelsea Young1, Faith D Ihekweazu1

  • 1Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.

The Journal of Pediatrics
|February 8, 2025
PubMed

Insights

Racial and ethnic disparities exist in pediatric inflammatory bowel disease (IBD). Hispanic children with IBD face higher hospitalization and emergency department use, highlighting the need for equitable care.

Area of Science:

  • Pediatric Gastroenterology
  • Health Disparities Research
  • Inflammatory Bowel Disease (IBD) Etiology

Background:

  • Pediatric inflammatory bowel disease (IBD) affects diverse populations.
  • Understanding racial and ethnic variations in IBD presentation and outcomes is crucial for equitable healthcare.
  • Previous research indicates potential disparities in disease management and patient outcomes across different demographic groups.

Purpose of the Study:

  • To investigate racial and ethnic disparities in disease phenotype, treatment, and outcomes among children with pediatric IBD.
  • To compare demographic factors, disease characteristics, and healthcare utilization across racial and ethnic groups in a pediatric IBD cohort.

Main Methods:

  • A cohort of 97 pediatric patients (ages 7-18) diagnosed with IBD between March 2020 and June 2021 was analyzed.
  • Patients self- or parent-identified as non-Hispanic (NH) Black, NH-White, or Hispanic.
  • Data on demographics, Social Vulnerability Index, Childhood Opportunity Index, disease phenotype, time to diagnosis, treatment, and healthcare utilization were compared between groups.

Main Results:

  • Hispanic patients had a higher prevalence of ulcerative colitis compared to non-Hispanic White patients.
  • Hispanic children with IBD were significantly more likely to be hospitalized at diagnosis.
  • Hispanic patients experienced more emergency department visits within two years of diagnosis compared to NH-White patients.

Conclusions:

  • Race and ethnicity appear to influence the diagnosis and treatment of pediatric IBD.
  • Findings suggest a need for further research in larger cohorts to validate these disparities.
  • Establishing equitable care practices for pediatric IBD patients is essential, informed by these observed differences.
Abstract

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
304
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
126
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
171
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
99
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
384
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
132