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Risk of developing sleep disorders and psychologic comorbidity in children with inflammatory skin diseases-A
Caroline Mann1, Andreas Wollenberg2, Sascha Ständer3
1Department of Dermatology, University Medical Center Mainz, Mainz, Germany.
Insights
Children with inflammatory skin diseases like atopic dermatitis, psoriasis, and urticaria face higher risks of sleep and mental health issues. Early screening and treatment are crucial for better health outcomes.
Area of Science:
- Pediatric Dermatology
- Sleep Medicine
- Mental Health Research
Background:
- Inflammatory skin diseases (ISDs) such as atopic dermatitis (AD), psoriasis, and urticaria are linked to mental health and sleep disturbances.
- The specific risks of these comorbidities in children remain under-evaluated.
Purpose of the Study:
- To evaluate the risk of sleep and psychological disorders in children diagnosed with inflammatory skin diseases.
Main Methods:
- Retrospective analysis of electronic health records from a US Collaborative Network.
- Propensity score matching was used to compare patients with AD, psoriasis, or urticaria against a control cohort.
Main Results:
- Children with psoriasis showed increased risks of hypersomnia (3.2x), sleep apnea (2.1x), fatigue (1.8x), and depression (1.9x).
- Children with urticaria or AD had higher risks of sleep disorders (1.7x), anxiety disorders (1.6x), and insomnia (1.4x). AD patients specifically had a 1.5x higher risk of anxiety disorders.
Conclusions:
- Children with ISDs exhibit a significantly higher risk for sleep and psychological disorders.
- Regular screenings and timely interventions are recommended to mitigate potential long-term mental and physical health consequences, improving quality of life.
Background:
Inflammatory skin diseases such as atopic dermatitis (AD), psoriasis, and urticaria are associated with impaired mental health and sleep. In children the risk of developing these comorbidities is still poorly evaluated.
Methods:
Retrospective data analysis of a US Collaborative Network including children of 55 health care providers was performed. Data from electronic health records of patients with a diagnosis of either AD, psoriasis, or urticaria, as well as a control cohort were retrieved in an anonymized batch format and propensity score matched.
Results:
Children with psoriasis had a 3.2-fold higher risk of hypersomnia, 2.1-fold higher risk of sleep apnea, 1.8-fold higher risk of fatigue, and 1.9-fold higher risk of depression. Children with urticaria (acute or chronic) and AD had a 1.7-fold higher risk of sleep disorders, 1.6-fold higher risk of anxiety disorders, and 1.4-fold higher risk of insomnia. AD children had a 1.5-fold higher risk of anxiety disorders.
Limitations:
Electronic health insurance data are not subject to random sampling of the general population and potential misdiagnosis is possible.
Conclusions:
Children with inflammatory skin diseases were at a higher risk of sleep psychological disorders. Thus, regularly performed screenings and appropriate treatment initiation might potentially prevent mental and physical health consequences and secure improved life quality.
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