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Updated: May 28, 2025
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
[The application of low-temperature plasma minimally invasive therapy in children with pharyngeal neoplasm]
1Department of Otolaryngology，Wuhan Children's Hospital（Wuhan Maternal and Child Healthcare Hospital.
Insights
Pediatric pharyngeal neoplasms often cause upper airway obstruction. Low-temperature plasma minimally invasive surgery offers a safe and effective treatment option for these conditions in children.
Area of Science:
- Otolaryngology
- Pediatric Oncology
- Minimally Invasive Surgery
Context:
- Pharyngeal neoplasms in children present unique diagnostic and therapeutic challenges.
- Early symptoms like throat wheezing and dyspnea can indicate serious underlying conditions.
- A variety of benign and malignant tumors can affect the pediatric pharynx.
Purpose:
- To analyze clinical features of pediatric pharyngeal neoplasms.
- To evaluate the efficacy of low-temperature plasma minimally invasive treatment for these tumors.
Summary:
- This study reviewed 46 pediatric pharyngeal neoplasm cases, identifying common symptoms such as throat wheezing and dyspnea.
- Pathological diagnoses included pharyngeal cysts, non-Hodgkin's lymphoma, and rhabdomyosarcoma.
- All patients underwent low-temperature plasma minimally invasive surgery, demonstrating its safety and effectiveness.
Impact:
- Low-temperature plasma radiofrequency ablation is a safe, precise, and minimally invasive option for pediatric pharyngeal neoplasms.
- Early diagnosis and treatment improve quality of life and survival rates in affected children.
- This approach facilitates a clear surgical field, aiding in complex pediatric head and neck procedures.
Abstract:
Objective:Analyze the clinical features in children with pharyngeal neoplasm, and explore the clinical efficacy of low-temperature plasma minimally invasive treatment in children with pharyngeal neoplasm. Methods:A total of 46 pediatric cases of pharyngeal neoplasms admitted to the Otolaryngology Department of Wuhan Children's Hospital from January 2016 to December 2023 were included. There were 23 males and 23 females, with admission ages ranging from 5 days to 9 years and 4 months, and a median age of 2 years and 2 months. The clinical manifestations, examinations, treatments, and outcomes were evaluated. Results:Among the 46 pediatric patients, 21 were admitted with throat wheezing, 7 with masses in the oropharynx or head and neck, 5 with dyspnea, 4 with snoring during sleep as the main symptom, 3 with hoarseness, 2 with sore throat, 2 with swallowing discomfort, and 2 with difficulty feeding as the first symptom. Comorbidities included 5 cases of combined laryngomalacia, 4 of snoring, 4 of congenital heart disease, 4 of severe pneumonia, 3 of myocardial damage, 1 of multiple deformities, and 1 after hematopoietic stem cell transplantation. All patients underwent CT or MRI examination, with 26 cases undergoing local ultrasound examination and 39 undergoing electronic laryngoscopy examination. A total of 19 patients were transferred to the ICU after surgery, all of whom were patients with pharyngeal cysts. All patients underwent low-temperature plasma minimally invasive surgery, and all patients were diagnosed through pathological examination, including 1 case of nasopharyngeal teratoma, 5 of pharyngeal non-Hodgkin's lymphoma, 1 of oropharyngeal rhabdomyosarcoma, 1 of laryngeal perivascular epithelioid cell tumor （PEComa）, and 38 of pharyngeal cysts （2 cases of uvula, 2 of oropharynx, 7 of epiglottic valley, 19 of tongue base, 2 of branchial cleft cyst, and 6 of throat）. Conclusion:Pharyngeal neoplasms in children are prone to upper airway obstruction, including some rare or malignant tumors. Imaging and pathological diagnosis can assist in early diagnosis. Depending on the nature of the tumor, early detection and treatment can improve the quality of life and survival rate of children. Low-temperature plasma radiofrequency ablation is safe, minimally invasive, precise, and provides a clear field of vision, making it a valuable treatment option for children with pharyngeal neoplasms.
