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Updated: May 28, 2025

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Rat Model of Adhesive Capsulitis of the Shoulder
Published on: September 28, 2018
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To evaluate repaired rotator cuff morphologically and quantitatively in one GRAPPATINI MRI examination
Yuxue Xie1, Jiajie Cai1, Qing Li2
1Department of Radiology & Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, Shanghai, PR China.
Acta Radiologica (Stockholm, Sweden : 1987)
|February 10, 2025
Summary
GRAPPATINI MRI provides simultaneous T2-weighted images and T2 maps for rotator cuff repair assessment. This efficient tool accurately evaluates morphology and predicts clinical outcomes post-surgery.
Area of Science:
- Radiology
- Orthopedic Surgery
- Medical Imaging
Background:
- GRAPPATINI is a novel MRI technique capable of generating synthetic T2 images (T2synth) and T2 maps within a single scan.
- Assessing repaired rotator cuffs (RC) requires both morphological and quantitative evaluations, often necessitating multiple imaging sequences.
Purpose of the Study:
- To evaluate the performance of GRAPPATINI in simultaneously assessing the morphology of repaired rotator cuffs (RC) using T2synth images.
- To quantitatively evaluate postoperative clinical outcomes by analyzing T2 maps generated by GRAPPATINI.
Main Methods:
- Prospective examination of 45 individuals with repaired RC (postoperative >2 years) using GRAPPATINI MRI and collection of clinical scores.
- Image quality assessed via contrast-to-noise ratio (CNR) of T2synth vs. conventional T2-weighted (T2W) images.
- Two blinded readers graded RC repairs using Sugaya classification on both T2synth and T2W images; T2 values correlated with clinical scores.
Main Results:
- GRAPPATINI acquired both T2synth and T2 maps in a clinically feasible time (2:18 min).
- No significant difference in CNR between T2synth and conventional T2W images (P=0.9).
- Inter-rater agreement for Sugaya classification was similar for T2synth and T2W images (P=0.8); T2 values correlated significantly with functional outcomes (r=0.39-0.52, P<0.05).
Conclusions:
- GRAPPATINI provides comprehensive morphological and quantitative shoulder assessment in a single MRI scan.
- The technique is efficient for evaluating rotator cuff repair status and predicting functional outcomes after arthroscopic repair.
Keywords:
Quantitative magnetic resonance imagingarthroscopic rotator cuff repairclinical outcomesrepair status
