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Transcranial Magnetic Stimulation in Pregnancy: Efficacy, Safety, and Future Implications for Perinatal Mental Health
Serena Angeline1, Babangida Tiyatiye2, Wole Akosile3
1Prince Charles Hospital, Metro North Mental Health, Brisbane, Queensland, Australia.
Introduction:
Repetitive transcranial magnetic stimulation (TMS) has gained interest as a treatment for major depressive disorder (MDD). However, the literature on its efficacy and safety for pregnant patients with MDD is limited. This article reviews and appraises available studies on TMS in pregnant women with MDD.
Methods:
We reviewed randomized controlled trials and open-label studies on TMS in pregnant women with MDD.
Results:
Studies indicate that TMS is a safe and effective treatment for MDD during pregnancy, showing significant reductions in depression scores and increased response and remission rates compared to sham TMS. TMS was well tolerated with minimal side effects.
Conclusion:
Larger, multicenter trials are needed to develop evidence-based protocols for TMS use in pregnancy.
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