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From Tics to Stabs: Renaming Cluster Tics in Cluster Headache-A Cross-Sectional Study
May Carney1, Marie-Louise Kulas Søborg1, Stine Maarbjerg1
1Department of Neurology, Danish Headache Center, University of Copenhagen, Rigshospitalet-Glostrup, Glostrup, Denmark.
European Journal of Neurology
|February 10, 2025
Summary
Nearly half of cluster headache patients experience "cluster tics," distinct from trigeminal neuralgia. These non-triggerable, orbital pains warrant renaming to "cluster stabs" for clarity.
Area of Science:
- Neurology
- Headache Medicine
- Pain Research
Background:
- Short-lasting facial pain paroxysms in cluster headache are often termed "cluster tics."
- These symptoms are frequently associated with trigeminal neuralgia but may represent an independent phenomenon.
- The distinct nature and prevalence of cluster tics require further investigation.
Purpose of the Study:
- To determine the prevalence of cluster tics in patients with cluster headache.
- To differentiate cluster tics clinically from trigeminal neuralgia.
- To propose a new definition and name for cluster tics.
Main Methods:
- A retrospective, controlled, cross-sectional study.
- Semi-structured interviews with 424 cluster headache patients.
- Inclusion of 576 trigeminal neuralgia patients for comparison.
Main Results:
- Cluster tics were reported by 47% of cluster headache patients.
- Higher prevalence observed in females and those with chronic cluster headache.
- Cluster tics were non-triggerable and localized to the first trigeminal division, unlike trigeminal neuralgia.
Conclusions:
- Cluster tics are common in cluster headache, particularly in females and chronic cases.
- Key differences from trigeminal neuralgia include non-triggerability and orbital pain location.
- The term "cluster stabs" is proposed to improve diagnostic clarity.

