Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Panic disorder and suicide.

Shih-Jen Tsai1,2, Chih-Ming Cheng1,2, Wen-Han Chang1

  • 1Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.

Psychological Medicine
|February 10, 2025
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Suicide attempt risk among patients receiving methylphenidate: a retrospective cohort study.

Psychopharmacology·2026
Same author

Distinct effects of current suicidal symptoms and lifetime suicide attempts on C-reactive protein levels and executive function in young people with major affective disorders.

European archives of psychiatry and clinical neuroscience·2026
Same author

Risks and Familial Coaggregation of Autism Spectrum Disorder Among First-Degree Relatives of Individuals With Colorectal Cancer.

Psychiatry investigation·2026
Same author

Abnormal left prefrontal N100 and its relationship with fronto-limbic metabolism in major depressive disorder.

Translational psychiatry·2026
Same author

Distinct therapeutic profiles of ketamine in treatment-resistant depression: an exploratory analysis.

The international journal of neuropsychopharmacology·2026
Same author

Physical and Psychiatric Comorbidities and Their Influence on All-Cause and Suicide Mortality: A Longitudinal Study of 109,900 Young Patients with Schizophrenia.

CNS spectrums·2026
Same journal

Distinct and common subcortical functional connectivity revealed across three major psychiatric disorders - CORRIGENDUM.

Psychological medicine·2026
Same journal

Adversity as the key feature: neuroimaging profiles of subtypes from multiple depression risk factors.

Psychological medicine·2026
Same journal

Sorting the mind: cognitive enhancement through transcutaneous auricular vagus nerve stimulation: a systematic review and meta-analysis.

Psychological medicine·2026
Same journal

Depression and aging: insights from brain age prediction models.

Psychological medicine·2026
Same journal

An integrative NLP framework identifies multilevel linguistic phenotypes of schizophrenia across tasks.

Psychological medicine·2026
Same journal

Predicting functional remission after antipsychotic discontinuation: a real-world study in schizophrenia - ERRATUM.

Psychological medicine·2026
See all related articles
This summary is machine-generated.

Panic disorder (PD) independently increases suicide risk. Comorbidities like major depressive disorder (MDD) significantly elevate this risk further, highlighting the need for integrated mental health care.

Area of Science:

  • Psychiatry
  • Epidemiology
  • Public Health

Background:

  • Panic disorder (PD) is associated with increased suicidal ideation and behaviors, often due to co-occurring conditions like major depressive disorder (MDD).
  • Previous research has not definitively established a direct link between PD and suicide mortality.
  • Understanding this relationship is crucial for suicide prevention strategies.

Purpose of the Study:

  • To investigate the independent association between panic disorder and suicide risk.
  • To examine the impact of psychiatric comorbidities on suicide risk in individuals with PD.
  • To quantify the elevated risk of suicide associated with PD and its common comorbidities.

Main Methods:

  • Utilized Taiwan's National Health Insurance Research Database (2003-2017) to identify 171,737 individuals with PD and matched controls.
Keywords:
Taiwanmajor depressive disorderpanic disorderpsychiatric comorbiditysuicide

Related Experiment Videos

  • Assessed suicide risk over the study period, considering comorbidities like schizophrenia, bipolar disorder, MDD, OCD, autism, AUD, and SUD.
  • Employed time-dependent Cox regression models to analyze suicide risk, adjusting for demographic factors and psychiatric comorbidities.

    • Main Results:

    • Panic disorder was confirmed as an independent risk factor for suicide (HR=1.85, 95% CI=1.59-2.14).
    • Major depressive disorder (MDD) in conjunction with PD showed the highest suicide risk (HR=6.08, 95% CI=5.48-6.74).
    • Other significant comorbidities increasing suicide risk included autism, schizophrenia, bipolar disorder, AUD, SUD, and OCD.

    Conclusions:

    • Panic disorder is a significant independent predictor of suicide.
    • The presence of psychiatric comorbidities, particularly MDD, substantially amplifies suicide risk in individuals with PD.
    • These findings underscore the importance of managing comorbidities in PD patients for effective suicide prevention.