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Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

84
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
84
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

64
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
64
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

324
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
324
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

60
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
60
Antihypertensive Drugs: Thiazide-Class Diuretics01:15

Antihypertensive Drugs: Thiazide-Class Diuretics

523
Thiazide diuretics are sulfonamide derivatives featuring a benzothiadiazine ring system in their molecular structure. Based on this structure, thiazide diuretics can be categorized into two groups: thiazide-type and thiazide-like diuretics. Thiazide-type diuretics, including hydrochlorothiazide and chlorothiazide, consist of a benzothiadiazine backbone with an attached sulfonamide group. Thiazide-like diuretics, such as chlorthalidone and indapamide, lack the thiazide ring but demonstrate...
523
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

149
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
149

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Related Experiment Video

Updated: May 28, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
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Recurrent Acute Pancreatitis Associated With Hydrochlorothiazide Use: A Case Report.

Benjamin K Linkous1,2, Angeli J Canekeratne1,2, Mohamed Naas1

  • 1Medical School, Florida State University College of Medicine, Tallahassee, USA.

Cureus
|February 10, 2025
PubMed
Summary

Drug-induced acute pancreatitis (DIAP) is rare but challenging. Hydrochlorothiazide (HCTZ) was identified as the cause in a patient with recurrent pancreatitis, resolving after discontinuation.

Area of Science:

  • Gastroenterology
  • Pharmacology
  • Internal Medicine

Background:

  • Acute pancreatitis (AP) is a common pancreatic inflammation, typically caused by gallstones or alcohol.
Keywords:
acute pancreatitisadverse drug reactiondrug-induced acute pancreatitismedication reconciliationsevere pancreatitisthiazide diureticsthiazide-associated pancreatitis

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  • Drug-induced acute pancreatitis (DIAP) is an uncommon but significant diagnostic challenge.
  • Requires careful medication review and high clinical suspicion for diagnosis.