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Updated: May 5, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
An unusual pathology of a nasal tip mass in a 28-year-old female
Shahin Rajaeih1, Farshad Riahi2, Behnaz Bouzari3
1ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, Firoozgar Hospital, Iran University of medical Sciences, Tehran, Iran.
Abstract:
The nose is a frequently affected site for skin cancers, thus it should always be considered when addressing pathologies of the external apex nasi. This case report presents a 28-year-old woman with an atypical nasal tip mass, characterized as a keratinous cyst demonstrating a multinucleated giant cell reaction and calcification. The mass, which had gradually enlarged over 3 years, was successfully removed using an open rhinoplasty technique. Preoperative imaging studies, including ultrasound, noncontrast CT, and MRI, revealed specific characteristics of the mass, aiding in diagnosis and surgical planning. The study underscores the need for increased awareness about nasal tip deformities caused by keratinous cysts, emphasizing the need for comprehensive diagnostic and therapeutic strategies to improve patient outcomes.

