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Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study
Ritesh Upadhyay1, Annasaheb J Dhumale2, Chanchlesh Dehariya3
1Department of Community Medicine, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
Journal of Pharmacy & Bioallied Sciences
|February 10, 2025
Summary
This study found no significant differences in clinical, laboratory, or sociodemographic factors between Plasmodium vivax and Plasmodium falciparum malaria cases in India. Further research is needed to understand these malaria infections.
Area of Science:
- Medical Research
- Infectious Diseases
- Public Health
Background:
- The National Malaria Elimination Program (NMEP) has reduced malaria mortality in India.
- Anemia poses a significant mortality risk in specific Indian regions.
Purpose of the Study:
- To evaluate clinical, laboratory, and sociodemographic factors linked to Plasmodium falciparum and Plasmodium vivax malaria.
- To compare these factors between P. vivax and P. falciparum infections.
Main Methods:
- A retrospective, record-based clinical study was conducted.
- Malaria cases were categorized into P. vivax and P. falciparum.
- Clinical, laboratory, and sociodemographic data were statistically analyzed.
Main Results:
- 222 malaria cases were analyzed; 74.48% P. vivax and 22.52% P. falciparum.
- Hepatomegaly was more frequent in P. falciparum; splenomegaly in P. vivax.
- Thrombocytopenia occurred in 58.1% of P. vivax and 72% of P. falciparum cases.
Conclusions:
- No statistically significant differences were observed in clinical, laboratory, or sociodemographic factors between P. falciparum and P. vivax malaria.
- These findings suggest a need for further investigation into the distinct aspects of these malaria types.
