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Three-Dimensional Bioprinting as a Tool for Tissue Engineering: A Review
Sneha C Dare1, Pavan S Bajaj1, Anand N Wankhede1
1Department of Periodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India.
Journal of Pharmacy & Bioallied Sciences
|February 10, 2025
Summary
Three-dimensional (3D) bioprinting uses living cells and biomaterials to precisely create tissues for regenerative therapy. This review explores 3D bioprinting advancements and applications in dentistry, including future 4D bioprinting.
Area of Science:
- Biotechnology and Regenerative Medicine
- Tissue Engineering
- Biomaterials Science
Background:
- Three-dimensional (3D) bioprinting is gaining traction in reconstructive and regenerative therapy.
- It employs 3D printing and bio-inks with living cells to engineer tissues.
- This technology offers precise control over construct creation for tissue regeneration.
Purpose of the Study:
- To review advancements in 3D bioprinting techniques.
- To discuss applications of 3D bioprinting in regenerative and reconstructive dentistry.
- To explore future perspectives, including 4D bioprinting.
Main Methods:
- Review of current literature on 3D bioprinting in tissue engineering.
- Analysis of bio-ink components and printing strategies.
- Examination of clinical and preclinical applications in maxillofacial reconstruction.
Main Results:
- 3D bioprinting enables precise fabrication of complex tissue structures.
- It offers significant potential for treating maxillofacial abnormalities.
- The technology provides control over spatial arrangement of cells and biomaterials.
Conclusions:
- 3D bioprinting is a promising alternative for tissue regeneration and reconstruction.
- Its applications in dentistry are expanding, offering new therapeutic avenues.
- Future developments, such as 4D bioprinting, hold further potential for regenerative medicine.
