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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Recent Bacteriological Trends and Emerging Antimicrobial Resistance among Hospitalized Patients in a Tertiary Care
Ankita Dixit1, Balvir Singh2, Priyanka Chaubey3
1Department of Pharmacology, L.N Medical College, Bhopal, Madhya Pradesh, India.
Background:
Emergence of antimicrobial resistance (AMR) is a major health concern worldwide. Knowledge about common hospital organisms and their antibiograms play a crucial role in minimized mortality caused by multidrug resistance organisms (MDROs).
Aim:
This study determines the bacteriological trends and antibiotic resistance patterns of various clinical samples among hospitalized patients.
Methods:
Various clinical specimens were received and processed for culture and identification as per standard operating procedures (SOPs). Antimicrobial susceptibility tests (ASTs) were performed as per standard guidelines.
Results:
The prevalence of aerobic bacterial isolates was 31.68%. The most common bacterial isolates were Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Klebsiella species, and Pseudomonas species. The majority of isolates were MDROs.
Conclusion:
Regular surveillance of MDRO helps in implementing better therapeutic strategies to reduce morbidity and mortality associated with them.
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