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Comparative Study of Different Irrigation Protocols in Endodontic Treatment
Midhun Paul1, Rekha V Ravi2, Chintu Sundaresan3
1Department of Conservative Dentistry and Endodontics, St Gregorios Dental College, Kothamangalam, Kerala, India.
Journal of Pharmacy & Bioallied Sciences
|February 10, 2025
Summary
Sodium hypochlorite (5.25%) is the most effective irrigant for endodontic treatment, significantly reducing bacteria and removing debris and smear layer compared to Chlorhexidine and EDTA.
Area of Science:
- Endodontic treatment
- Microbiology
- Dental materials science
Background:
- Root canal irrigation is crucial for removing bacteria, organic tissue, and debris.
- Effective irrigation protocols enhance endodontic treatment outcomes.
Purpose of the Study:
- To compare the efficacy of three different irrigation protocols in endodontic treatment.
- To evaluate the removal of bacteria, debris, and smear layer using sodium hypochlorite, Chlorhexidine, and EDTA.
Main Methods:
- An in vitro study involving 60 extracted single-rooted human teeth.
- Teeth were divided into three groups, each treated with a different irrigant: 5.25% sodium hypochlorite, 2% Chlorhexidine, or 17% EDTA.
- Microbiological techniques and scanning electron microscopy (SEM) were used to assess irrigation efficacy.
Main Results:
- Sodium hypochlorite (5.25%) demonstrated the highest mean log reduction in bacterial load (4.77 ± 0.54).
- SEM analysis showed 85% cleanliness for sodium hypochlorite, compared to 70% for Chlorhexidine and 50% for EDTA.
- Sodium hypochlorite significantly outperformed Chlorhexidine and EDTA in bacterial reduction and debris/smear layer removal (P < 0.05).
Conclusions:
- 5.25% sodium hypochlorite is the most effective irrigant for endodontic procedures.
- This irrigant excels in reducing bacterial count and flushing out root canal debris and smear layer.
Keywords:
ChlorhexidineEDTAIrrigation solutions and proceduresdisinfection of the root canal space and residual removalsmear layersodium hypochloriteMore Related Videos
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