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An enzyme-free fluorescence biosensor for UO22+ detection using Y-shaped wheel-mediated triple walking as a signal
Ying Zeng1, Yuyan Wang1, Xiaoya Ren1
1Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China.
Abstract:
Based on a Y-shaped wheel-mediated triple walker, an enzyme-free biosensor was reported for UO22+ detection. Due to the DNAzyme-driven mechanism, our walker was activated and produced a fluorescence signal for UO22+ assay. The sensor demonstrated ultra-sensitivity, good specificity and excellent accuracy, holding great promise for UO22+ sensing in complex water samples.

