Related Experiment Video
Updated: May 28, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
Tackling the growing burden of nitrous oxide-induced public health harms
Safiya A Zaloum1, Devan Mair1, Alvar Paris2
1Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Abstract:
Nitrous oxide has been increasing in popularity as a recreational drug in the past decade, and with this an increase in health harms related to nitrous oxide use, particularly nitrous oxide-induced myeloneuropathy. In response, governments in many countries have adopted new laws that either target the end user, by criminalising possession, or target suppliers. The effect of these measures remains to be seen, but the potential to exacerbate harm by targeting the user and thus affecting health-care-seeking behaviour is a concern. Education around the preventable harm from recreational use of nitrous oxide and tightening regulations on suppliers are essential in mitigating the increase in nitrous oxide-related health harms.
Related Concept Videos
Inhalational Anesthetics: Overview
2° Amines to N-Nitrosamines: Reaction with NaNO2
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by...
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

