A further example of IgM anti-K2 (Cellano)

An example of a cold-reacting IgM anti-K2 is described. The patient has a history of blood transfusion and two pregnancies. It is, therefore, not possible to differentiate between natural occurrence or immune stimulation as an explanation of this antibody's presence. In 1966, Thomas and Konugres reported an unusual example of anti-K2 composed entirely of IgM and reacting optimally at 20 degrees C, although some reactions at 37 degrees C were observed. We wish to report a further example which does not react at 37 degrees C.