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Updated: Apr 30, 2026

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices
Published on: May 9, 2018
[Pulmonary function tests in a population with endemic pleural plaques and environmental asbestos exposure]
Abstract:
The prevalence of pleural plaques in a sample of a community subjected to environmental asbestos exposure from natural deposits was 10%. Spirogram, flow-volume curves and pulmonary resistance of persons with plaques were not significantly different from controls. The larger, age-dependent decrease in lung function parameters in our sample as compared with various reference values may be explained by accelerated "aging" of the bronchial tree related to exposure to the noxious inhalant or by underrepresentation of the higher age groups in the reference studies.
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